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How to Get a Nurse (RN/LPN) License in Missouri (2026)

Quick answer

Renewal opens March 1–May 31 of even years for LPNs and February 1–April 30 of odd years for RNs.

Renewal

LPN licenses expire on 5-31 of each even-numbered year. RN licenses expire on 4-30 of each odd-numbered year. A nurse is required to renew 3 business days before the expiration date.

View official source

Last verified Oct 25, 2026

How do I get this license?

  1. Check the licensing authority

    Board

    Missouri Board of Nursing

    Last verified Oct 25, 2026 — source and quotation
    Board of Nursing
    Official source

    Official agency page

    Open the official agency page

    Last verified Oct 25, 2026 — source and quotation
    Renewal Information
    Official source
  2. Prepare your application

    Apply with the agency

    Open the official agency page

    Last verified Oct 25, 2026 — source and quotation
    You will go to your account in the MOPRO portal at mopro.mo.gov/license/s/.
    Official source
  3. Confirm your next step with the agency

    Review the official instructions for your situation before applying.

    Open the official agency page

What else should I know?

Agency guidance

Renewal opens March 1–May 31 of even years for LPNs and February 1–April 30 of odd years for RNs.

Last verified Oct 25, 2026 — source and quotation
Your LPN license will be eligible for renewal every even-numbered year between March 1 and May 31. Your RN license will be eligible for renewal every odd-numbered year between February 1 and April 30.
Official source

Agency guidance

Maintain both a Nursys e-Notify account and a MOPRO account for renewal.

Last verified Oct 25, 2026 — source and quotation
You need to have two accounts. One with Nursys® e-Notify (national system) and the other with our licensing system (state system) called MOPRO.
Official source

When do I renew, and is CE required?

Renewal

LPN licenses expire on 5-31 of each even-numbered year. RN licenses expire on 4-30 of each odd-numbered year. A nurse is required to renew 3 business days before the expiration date.

Last verified Oct 25, 2026 — source and quotation
LPN licenses expire on 5-31 of each even-numbered year. RN licenses expire on 4-30 of each odd-numbered year. There is no grace period to renew. A nurse is required to renew 3 business days prior to the expiration date.
Official source

Have a license or permit? Use the expiration date printed on it to set up your calendar and reminders.

What does it cost?

Confirm the charges and conditions for your application with the official agency.

What are the common questions?

How often do I renew a registered nurse and lpn renewal and continuing education license in Missouri?

LPN licenses expire on 5-31 of each even-numbered year. RN licenses expire on 4-30 of each odd-numbered year. A nurse is required to renew 3 business days before the expiration date.

Source and quotation
LPN licenses expire on 5-31 of each even-numbered year. RN licenses expire on 4-30 of each odd-numbered year. There is no grace period to renew. A nurse is required to renew 3 business days prior to the expiration date.
Official source

Last verified Oct 25, 2026

Which official sources support this guide?

Official sources and verification (6)

Last verified Oct 25, 2026. Each quotation supports the corresponding published value.

Board

Missouri Board of Nursing

Missouri Board of Nursing

Board of Nursing
Official source

Last verified Oct 25, 2026

Official agency page

Open the official agency page

https://pr.mo.gov/nursing-renewal.asp

Renewal Information
Official source

Last verified Oct 25, 2026

Apply with the agency

Open the official agency page

https://mopro.mo.gov/license/s/

You will go to your account in the MOPRO portal at mopro.mo.gov/license/s/.
Official source

Last verified Oct 25, 2026

Agency guidance

Renewal opens March 1–May 31 of even years for LPNs and February 1–April 30 of odd years for RNs.

Renewal opens March 1–May 31 of even years for LPNs and February 1–April 30 of odd years for RNs.

Your LPN license will be eligible for renewal every even-numbered year between March 1 and May 31. Your RN license will be eligible for renewal every odd-numbered year between February 1 and April 30.
Official source

Last verified Oct 25, 2026

Agency guidance

Maintain both a Nursys e-Notify account and a MOPRO account for renewal.

Maintain both a Nursys e-Notify account and a MOPRO account for renewal.

You need to have two accounts. One with Nursys® e-Notify (national system) and the other with our licensing system (state system) called MOPRO.
Official source

Last verified Oct 25, 2026

Renewal

LPN licenses expire on 5-31 of each even-numbered year. RN licenses expire on 4-30 of each odd-numbered year. A nurse is required to renew 3 business days before the expiration date.

LPN licenses expire on 5-31 of each even-numbered year. RN licenses expire on 4-30 of each odd-numbered year. A nurse is required to renew 3 business days prior to the expiration date. Applies to: Missouri RN and LPN licenses; there is no grace period.

LPN licenses expire on 5-31 of each even-numbered year. RN licenses expire on 4-30 of each odd-numbered year. There is no grace period to renew. A nurse is required to renew 3 business days prior to the expiration date.
Official source

Last verified Oct 25, 2026

Not yet verified: license fee, required hours, exam, continuing education — see the official agency.

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What should I explore next?

Registered nurse and LPN renewal and continuing education in neighboring states

Neighboring states use Census adjacency data, including water and point boundaries.

Related licenses in Missouri

What’s my next step?

Last verified Oct 25, 2026.

Official sources (1)

Not legal or tax advice. Confirm with the official agency before filing.